Intestinal Flora and Vitamin B1
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Response of Intestinal Bacterial Flora to the Long-Term Feeding of Aflatoxin B1 (AFB1) in Mice
In order to investigate the influence of aflatoxin B1 (AFB1) on intestinal bacterial flora, 24 Kunming mice (KM mice) were randomly placed into four groups, which were labeled as control, low-dose, medium-dose, and high-dose groups. They were fed intragastrically with 0.4 mL of 0 mg/L, 2.5 mg/L, 4 mg/L, or 10 mg/L of AFB1 solutions, twice a day for 2 months. The hypervariable region V3 + V4 on ...
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Commensal microorganisms are not ignored by the intestinal immune system. Recent evidence shows that commensals actively participate in maintaining intestinal immune homeostasis by interacting with intestinal epithelial cells and delivering tolerogenic signals that are transmitted to the underlying cells of the immune system.
متن کاملB1 cells contribute to serum IgM, but not to intestinal IgA, production in gnotobiotic Ig allotype chimeric mice.
B1 cells are a significant source of natural serum IgM, thereby serving as a first line of defense against systemic bacterial and viral infections. They can migrate to the intestinal lamina propria and differentiate into IgA-producing plasma cells and thus might play a similar role in mucosal immunity. To investigate the contribution of B1 cells to the intestinal IgA response induced by the com...
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The chicken is an animal of great economic importance and is widely used in the assay of certain vitamins, but little is known about its intestinal flora. The first study of the microbial flora of the chicken's intestinal tract was conducted by Kern (1897). His investigations embraced not only the chicken and other gallinaceous birds, but many of the common wild birds. Other work on the microfl...
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